PLATFORM AND TECHNOLOGY

Core Technology

Currently, there are more than 10 ongoing projects designed by strategies of UCAR-T/NK、PrimeCAR、PrecisionCAR、ResCAR、PhiCAR and HyeCAR Technique, including common hematologic tumors, solid tumors and multiple pipeline products of General CAR.
UCAR-T/NK Convenient and fast, high uniformity
C-1-144
C-2-90
U-1-2
C-35-X
The leading LstCAR universal CAR-T solution; unique CAR-NK vector design, efficient NK transduction and in vitro expansion, to create a convenient, fast, and high uniformity of universal CAR cell products.
PrecisionCAR Humanized structure, high effectiveness
pCAR-19B
Advanced humanized design, optimizationof full vector and full linker , ImmEVL immunogenicity evaluation system suitable for Chinese population, to create more effective CAR-T products.
PRIMCAR®® High safety and long-lasting efficacy
D-2-27
Faster and more effective CAR-T preparation scheme; lower dose, less side-effect, and more durable human therapeutic effects; all efforts are made only to ensure that patients are more accessible.
RESCAR® Targeting the tumor immune microenvironment
C-13-90
C-37-X
Solutions of tumor immunosuppressive microenvironment , say "no" to the suppression signal , and stimulate potential in a repressed environment.

· Serial immune checkpoint conversion design solutions, patent layout at home and abroad

· Pre-clinical functional verification of various cancer PDX showed that the anti-tumor activity was significantly enhanced
PhiCAR® Make breakthroughs in the tumor physical microenvironment
C-13-60
Solutions of addressing CAR-T tumor arrival and survival in the tumor microenvironment.

· Promotes tumor aggregation of CAR-T and reduces side effects at non-tumor sites

· Reduce the loss of CAR-T in the non-working state, and maximize the anti-tumor effect

· Adapt to the tumor physical microenvironment.
HyeCARTM Recognition of multiple antigens, prevention of relapse
C-4-29
D-2-27
Multi-target CAR technology, which can simultaneously independently or cooperatively target different targets or multiple epitopes of the same target.

· Multi-target independent recognition

· Multi-target functional synergy

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